Welcome to Gameday Men’s Health Clinic Downtown San Francisco, CA

Our men’s health clinic in Downtown San Francisco, CA, offers testosterone replacement therapy (TRT), erectile dysfunction treatment, medical weight loss, longevity care, peptide therapy and vitamin injections, hair loss treatment, and sports injury care.

Visit our Downtown San Francisco TRT clinic at 465 California St, Suite 610, San Francisco, CA 94104. We welcome men from Pacific Heights, Embarcadero and Mission Bay. Same-day labs and results. No insurance needed.

Modern Gameday Men’s Health clinic waiting area with seating and large windows

Why Choose
Gameday Men's Health Downtown San Francisco

Our clinic was built around one simple idea: men deserve a modern, personalized approach to healthcare. We go beyond routine checkups to address the full picture of your well-being—physical, mental, and lifestyle. At Downtown San Francisco we offer:
Personalized Care
On-site lab testing
Ongoing Support
Flexible Appointments
Comfortable Spaces
Life-changing treatments

Meet Your Downtown San Francisco Clinical Care Team

Andrew Nguyen, PA-C, MPH

Andrew Nguyen

PA-C, MPH

Gameday vs Everyone Else

Because men deserve better care — fast, personal, and built around results.

The Other Guys

Traditional Medicine

Dedicated Clinician

Real In-Clinic Care

Men's health experts

Root-cause treatments

Same-day labs

Comfortable, private visits

Ongoing Monitoring

Long-term support

Real Results from Men's Health Patients in Downtown San Francisco

4.9
Across +400 clinics
“Many men hate going to the Doctor to discuss some of their personal issues. Run! Don’t walk into this place if you’re looking for a clinician to actually listen to you.”
– Clark G.
4.9
Across +400 clinics
Business man talking on the phone to book an appointment.Business man talking on the phone to book an appointment.

Need Help Booking
Your Visit?

Talk to a real person at Downtown San Francisco —
we’ll answer your questions and schedule your appointment.

What to Expect at Your First Visit in Downtown San Francisco

The average American spends about 18 minutes a year with their primary care doctor. Your first Gameday visit is a face-to-face deep dive — with labs, results, and a personalized protocol before you leave.
A dedicated clinician who knows your history and goals
Immediate lab testing with same-visit results
Ongoing performance tracking and protocol optimization
Direct access to your clinician between visits
A frictionless, concierge-level experience
Transparent cash-pay pricing
Getting here

In Financial District, on California St

Address

465 California St, Suite 610, San Francisco, CA 94104

Opening Hours
Mon
9:00am - 6:00pm
Tue
9:00am - 6:00pm
Wed
9:00am - 6:00pm
Thu
9:00am - 6:00pm
Fri
9:00am - 6:00pm
Sat
Closed
Sun
Closed
Drive times
  • From Union Square 8 min
  • From PIER 39 12 min
  • From Pacific Heights 12 min

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Questions About Visiting Our Downtown San Francisco Men's Health Clinic

Where can I get my testosterone tested in San Francisco?

San Francisco men who want their testosterone checked can book at Gameday Men's Health San Francisco any weekday from 9 am to 6 pm, and results come back the same day. Low T tests are done in Suite 610 at 465 California St, with no referral required. Book online or call (415) 319-6683.

What affects the cost of TRT at Gameday Men's Health San Francisco?

How much TRT (testosterone replacement therapy) costs at Gameday Men's Health San Francisco depends on the form you choose, such as testosterone injections or hormone pellets, and on how often you come back for follow-ups. Your labs, with results the same day, only show whether treatment is right for you. Pricing is transparent at the Suite 610 office. The clinic accepts HSA and FSA payments. Book online or call (415) 319-6683.

Where can I get GLP-1 weight loss treatment in San Francisco?

GLP-1 weight loss treatment in San Francisco is available at Gameday Men's Health San Francisco, Suite 610 at 465 California St, where the listed medication is semaglutide. Weight loss counseling is offered too. A clinician decides with you whether semaglutide fits after your evaluation and labs. Book online or call (415) 319-6683.

Where can I get testosterone replacement therapy (TRT) in San Francisco?

Clinicians at Gameday Men's Health San Francisco can prescribe testosterone replacement therapy (TRT) once your evaluation and labs show it's right for you, and those labs come back the same day. Hormone pellet therapy is one listed option, and your follow-ups stay in Suite 610 on California St. Book online or call (415) 319-6683.

Where can I get B12 and vitamin injections in San Francisco?

A vitamin deficiency test is a sensible first step if you're looking for a B12 shot in San Francisco, and Gameday Men's Health San Francisco lists one along with vitamin B12 and B complex injections. A clinician in Suite 610 goes over the results with you before recommending an injection. Book online or call (415) 319-6683.

What is Gameday Men's Health, and who runs the San Francisco clinic?

Gameday Men's Health is a network of men's health clinics, and Gameday Men's Health San Francisco is locally owned and operated. You'll find it in Suite 610 at 465 California St, with peptide therapy and vitamin injections such as B12 on its list next to testosterone care. Book online or call (415) 319-6683.

What should I bring to my appointment at Gameday Men’s Health in Downtown San Francisco?

Please bring a valid photo ID and any recent lab work if you have it. If you’re currently taking medications or supplements, it’s helpful to bring a list as well. Our team in Downtown San Francisco will walk you through everything else when you arrive.

Is parking available at the Downtown San Francisco clinic?

Yes, convenient parking is available near our Downtown San Francisco clinic. Specific parking details may vary by neighborhood, and our front desk can always help direct you to the best nearby options.

Can I start treatment the same day as my appointment?

In many cases, yes. Depending on your evaluation and lab results, same-day treatment may be available at our Downtown San Francisco clinic. Your provider will review your results and discuss next steps during your visit.

What happens during my first visit?

Your first appointment at our Downtown San Francisco clinic includes a consultation with a medical provider, a review of your health history, and diagnostic testing if needed. Based on your goals, we’ll outline personalized options and answer any questions you have before moving forward.

How long does an appointment usually take?

Most initial visits at our Downtown San Francisco clinic take about 45–60 minutes. Follow-up appointments are often shorter, depending on the services included.

Are consultations and treatments private?

Absolutely. Privacy and discretion are a top priority at our Downtown San Francisco clinic. All appointments, consultations, and treatments are handled in a confidential medical setting.

What services are available at the Downtown San Francisco clinic?

Our Downtown San Francisco clinic provides a comprehensive range of men’s health services, including:

• Testosterone Therapy

• Weight Loss

• Sexual Wellness & ED

• Anti-Aging & Longevity

• Peptides & Vitamins

• Hair Loss

• Sports Injury

Each service begins with a personalized consultation to ensure care is tailored to your health goals.

How often will I need to visit the clinic?

Visit frequency depends on your personalized plan. Some patients visit weekly or monthly, while others only need periodic check-ins. Your provider at the Downtown San Francisco clinic will explain what to expect.

Learn More About Men’s Health

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