A New Look Testosterone Therapy

Gameday Men’s Health West Hartford
August 5, 2024
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Article / A New Look Testosterone Therapy

A New Look At Testosterone Therapy In [location_name], CT

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Over the past ten years, there has been a notable surge in the use of testosterone replacement therapy (TRT) in [location_name], CT. Many older men have adopted TRT to balance their hormone levels, hoping to increase their energy and revive their sex drive.

Nevertheless, TRT remains controversial due to its ambiguous benefits and potential health hazards. Years ago, safety concerns emerged when research suggested a possible link between TRT and a higher incidence of cardiovascular disease.

According to Dr. Frances Hayes, a reproductive endocrinologist at Harvard-affiliated Massachusetts General Hospital, some of these studies were constrained by their limitations.

“For instance, in one study, TRT doses were much higher than what would usually be prescribed, and the subjects tended to be more frail, with other health problems,” she says. “Other studies showed no evidence of increased risk.”

THE LATEST FINDINGS

Recent discoveries have reinforced this perspective. Research unveiled at the 2015 American Heart Association Scientific Sessions involved 1,472 men aged 52 to 63 who had low testosterone levels and no prior history of heart disease.

Studies revealed that healthy men undergoing TRT did not demonstrate an elevated risk of heart attack, stroke, or death.

Additionally, findings from the August 2015 Mayo Clinic Proceedings indicated that there was no link between TRT and venous blood clots in a cohort of 30,000 men. “Right now, the jury is still out about TRT’s influence on cardiovascular disease,” says Dr. Hayes.

The link between TRT and other health concerns shows significant variability. While TRT has previously been associated with an elevated risk of prostate cancer, a study in the December 2015 issue of the Journal of Urology indicated that exposure to TRT over five years was not linked to an increased likelihood of aggressive prostate cancer.

There are persistent long-term uncertainties regarding the risks associated with TRT, largely due to inadequate follow-up in numerous studies. However, this does not mean that TRT should be completely avoided. It may still be a viable option for specific groups of men.

Who Is a Candidate For TRT In [location_name], CT?

In WEST HARTFORD, CT, obtaining a prescription for TRT requires meeting two conditions: testosterone levels below 600 nanograms per deciliter (ng/dL) and experiencing multiple symptoms (refer to page 7). Dr. Hayes explains, “While it’s possible to have low levels without symptoms, if you lack key symptoms, particularly fatigue and sexual dysfunction, it’s not advisable to start TRT due to current uncertainties surrounding its long-term safety.”

A standard blood test is used to measure testosterone levels. Due to daily fluctuations affected by medication and diet, multiple tests are often required. Dr. Hayes mentions, “In 30% of instances where the first testosterone test indicates low levels, subsequent tests show normal levels.”

Low testosterone levels and several symptoms don’t automatically mean testosterone replacement therapy (TRT) is the first recommended step. “Identifying the underlying cause of declining levels allows us to address it and naturally boost low levels,” states Dr. Hayes.

For example, weight gain is often the foremost reason behind declining levels.
“Weight exerts a more substantial influence on testosterone levels than aging. As weight increases, testosterone levels decrease,” she explains. Increasing your body mass index (BMI) by five points, such as from 30 to 35, is comparable to aging 10 years in terms of its effect on testosterone levels.

“Your doctor should also assess any additional factors that could impact levels, such as medication or medical conditions,” advises Dr. Hayes. In such cases, your doctor might address the root cause or modify your medication or dosage to avoid affecting testosterone levels.

Men should understand the limitations of TRT, as it is often seen as a panacea. “Its results are often less remarkable than many men envision,” notes Dr. Hayes.

Take sexual health and vitality, for instance, frequently promoted advantages of TRT. According to a study in the February 18, 2016 edition of The New England Journal of Medicine, researchers investigated TRT’s impact on 790 men aged 65 and above. Those administered TRT for a year, versus those given a placebo, reported enhancements in sexual function—activity, desire, and erectile function. Yet, the group saw only slight mood improvement and no changes in walking speed, a vitality measure associated with TRT.

Using TRT

Testosterone replacement therapy (TRT) is commonly administered via gel application or injections. With gels, a daily dose about the size of a ketchup packet is applied to the upper arms, shoulders, or thighs. Injections are typically given biweekly into the buttocks.

Each method has its own advantages, with gels providing more stable testosterone levels. “However, you must avoid close skin contact for a few hours, especially with women, as the testosterone can cause acne or hair growth,” advises Dr. Hayes.

With injections, testosterone levels may surge for several days following the injection and then gradually decrease. This can lead to a roller-coaster effect, where mood and energy levels peak and then decline.

Many men in WEST HARTFORD, CT see symptom improvement within four to six weeks, although changes like increased muscle mass may require three to six months.
Additionally, TRT may not be required for life. “If the cause of your low testosterone levels resolves, you should try stopping treatment and get re-evaluated by your doctor,” says Dr. Hayes.

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