A New Look Testosterone Therapy

Gameday Men’s Health Parker
July 25, 2024
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Article / A New Look Testosterone Therapy

A New Look At Testosterone Therapy In [location_name]

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Over the past decade, Parker has witnessed a significant rise in the popularity of testosterone replacement therapy (TRT). Numerous older men are opting for this treatment to restore their hormone levels, aiming to boost their energy and revive their sexual desire.

Although TRT is frequently utilized, it continues to be a contentious issue due to its uncertain benefits and potential health risks. Past studies suggested a possible connection between TRT and a higher risk of cardiovascular disease, prompting safety concerns.

Recognizing the limitations in certain studies, Dr. Frances Hayes, a Reproductive Endocrinologist at Harvard-affiliated Massachusetts General Hospital, offers her perspective.

“For instance, in one study, TRT doses were much higher than what would usually be prescribed, and the subjects tended to be more frail, with other health problems,” she says. “Other studies showed no evidence of increased risk.”

THE LATEST FINDINGS

New research supports this position. At the 2015 American Heart Association Scientific Sessions, a study involving 1,472 men aged 52 to 63 with low testosterone and no cardiovascular disease history revealed that TRT did not increase the risk of heart attack, stroke, or death in healthy men.

Further research published in the August 2015 Mayo Clinic Proceedings found no association between TRT and blood clots in veins among 30,000 men. “Right now, the jury is still out about TRT’s influence on cardiovascular disease,” says Dr. Hayes.

TRT’s link to other health issues remains inconclusive. Although previous studies associated TRT with a higher risk of prostate cancer, a December 2015 Journal of Urology study indicated no increased risk of aggressive prostate cancer with five years of TRT exposure. This challenges conventional wisdom and calls for further investigation into TRT’s long-term effects.

With limited follow-up in numerous studies, the long-term risks of TRT remain unclear. Still, TRT should not be dismissed as a potential solution, as it may be suitable for specific individuals.

Who Is a Candidate For TRT In [location_name]?

Parker mandates two requirements for TRT prescription: testosterone levels below 600 nanograms per deciliter (ng/dL) and experiencing multiple symptoms (refer to page 7). Dr. Hayes emphasizes, “While it’s conceivable to have low levels without symptoms, if crucial symptoms like fatigue and sexual dysfunction aren’t present, initiating TRT isn’t advisable due to current uncertainties surrounding its long-term safety.”

A common method to measure testosterone levels is through a blood test. Due to daily fluctuations and the influence of medication and diet, multiple tests are necessary. Dr. Hayes explains, “In around 30% of cases where the initial testosterone test indicates low levels, subsequent tests show normal levels.”

Even with low testosterone levels and various symptoms, testosterone replacement therapy (TRT) isn’t always the immediate solution. Dr. Hayes suggests “By understanding the underlying cause of declining levels, we can address it and naturally enhance low levels.”

As a case in point, TRT is frequently touted for its potential benefits in sexual well-being and vitality. According to a study published in the February 18, 2016 edition of The New England Journal of Medicine, 790 men aged 65 and older were studied to assess TRT’s effects. Those who received TRT for one year, compared to those on a placebo, reported enhancements in sexual function, including activity, desire, and erectile function. However, the group experienced only slight improvements in mood and noticed no changes in walking speed, which is an indicator of TRT’s impact on vitality.

“Your doctor should also consider any additional factors that could influence levels, such as medication or medical conditions,” recommends Dr. Hayes. In such circumstances, your doctor may address the underlying issue or adjust your medication or dosage to sidestep influencing testosterone levels.

It’s important for men to be aware of the limitations of TRT, frequently seen as a magical solution. “Its outcomes are typically not as astounding as men expect,” Dr. Hayes observes.

An example of this is the frequent emphasis on sexual health and vitality as benefits of testosterone replacement therapy (TRT). A study published in the February 18, 2016 release of The New England Journal of Medicine investigated the effects of TRT on 790 men aged 65 and older. Participants who received TRT for one year, compared to those on a placebo, observed improvements in sexual function, including activity, desire, and erectile function. However, the group only experienced a marginal improvement in mood and detected no changes in walking speed, a measure of TRT’s effect on vitality.

Using TRT

TRT can be administered via gel application or injection. Gel application requires spreading the daily dose, roughly the size of a ketchup packet, over both upper arms, shoulders, or thighs. Injections are typically administered into the buttocks every two weeks.

Both methods offer distinct advantages, with gels maintaining stable testosterone levels. “However, you should be careful to avoid close skin contact for a few hours, especially with women, as testosterone could cause acne or hair growth,” Dr. Hayes advises.

Following an injection, testosterone levels may briefly surge before tapering down, causing mood swings and energy fluctuations reminiscent of a roller-coaster.

In Parker, most men typically experience symptom improvement within four to six weeks, although changes in muscle mass might take three to six months.

TRT is not necessarily a lifelong commitment. “If the factor that caused your testosterone drop is resolved, you should try stopping the treatment and be re-evaluated by your doctor,” says Dr. Hayes.

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