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One in five American men over 20 has erectile dysfunction (ED), often known as impotence. Many psychological and physiological variables might contribute to erectile dysfunction. However, the general public has a limited understanding of the condition due to the stigma associated with discussing mental health issues.

On the other hand, erectile dysfunction is easily curable in many instances with the use of specific drugs that can make it easier to achieve and sustain an erection. The first thing you should do is consult a doctor who specializes in men’s health and discuss any difficulties you may be having maintaining an erection. Alterations to one’s way of life and one’s nutrition can also assist in promoting healthy erection function.

The overwhelming majority of men who seek therapy for erectile dysfunction (ED) discover that whatever previous performance anxiety they may have had disappears, and they experience a considerable improvement in their sex life.


Erectile dysfunction occurs when a man loses the ability to establish and maintain an erection while engaging in sexual activity. This might make it difficult for the male to have sexual satisfaction. It is not the same as premature ejaculation, which is when a man discharges semen before climaxing (having an orgasm) immediately after participating in sexual contact, leading him to lose his hardness. This condition is not the same as what we are talking about here.

Some guys may experience both ED and premature ejaculation at the same time. It is recommended to address erectile dysfunction initially because doing so will typically fix the problems with premature ejaculation as the treatment progresses.

Since ED involves the central nervous system (brain and spinal cord), cardiovascular system, and reproductive system, its physiological mechanisms are complex.

The brain’s neurotransmitters, namely epinephrine, dopamine, and acetylcholine, cause an erection. Both psychological and physical sexual stimulation sends electric signals to the vascular system, which sends blood to the penis. Two penile arteries deliver oxygen-rich blood to the corpora cavernosa and erectile tissue, expanding the penis due to pressure and blood flow.




Erectile dysfunction occurs when a man loses the ability to establish and maintain an erection while engaging in sexual activity.

During sexual engagement, erectile dysfunction occurs when a man lacks the capacity to initiate and maintain an erection.

Because blood must stay in the penis when in an erection to keep its stiffness and size, erectile tissue is encircled by fibrous elastic sheathes (tunicae), constricting and limiting blood flow from the penis. As a result, following orgasms or the cessation of stimulation, the pressure in the penis decreases, blood flow away from the penis increases, and the penis reverts to its flaccid state.

Medication for ED frequently aims at substances in the body that modulate these processes. By blocking phosphodiesterase-5 (PDE5) enzymes, drugs like sildenafil (Viagra) and tadalafil (Cialis) increase blood flow to the penis.

Penis blood vessel relaxation and increased blood flow are the results of PDE5 inhibitors maintaining the activity of intracellular messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in the corpus cavernosum.


Many men wrongly attribute ED to the natural consequences of becoming older, although this is not always the case. While aging and the related drop in testosterone are significant and can lead to erectile dysfunction, a variety of other variables must be considered.

In particular, the frequency of ED among such men with type-2 hypertension and diabetes is much greater than among healthy men.

This makes sense, considering that hypertension and type-2 diabetes can impede cardiovascular function and make it difficult for blood to circulate to the penis and produce an erection.

The treatment for erectile dysfunction (ED) is to remove whatever is causing it.

In fact, erectile dysfunction is highly linked to emotional and mental health, especially in younger men. Therefore, the term “psychogenic erectile dysfunction” describes these cases.

In fact, erectile dysfunction is highly linked to emotional and mental health, especially in younger men. Psychogenic erectile dysfunction is a term used to describe this condition.


Testosterone is the prototypical “man” hormone, and its androgenic qualities significantly impact arousal and erectile function, both directly and indirectly. Although various medical issues can result in erectile dysfunction, androgen insufficiency (low testosterone) is significant.

In both sexes, testosterone is a hormone that has far-reaching effects on the body (whether directly or indirectly). Low testosterone is effectively the beginning of a following vicious cycle of chronic health disorders that all feed into one another.

Studies suggest that erectile dysfunction is physiologically influenced by low T, which is associated with an increased risk of metabolic syndrome, type-2 diabetes, endothelial dysfunction, cardiovascular disease, and anemia.

Depression and other mood disorders are also known to have a negative effect on libido and erection quality, and they are related to a lower T level.

TRT can aid in the treatment of erectile dysfunction by restoring men with low T to a state of emotional and psychological health and self-assurance. 

In other words, to find a cure for erectile dysfunction that will be effective over the long term, a guy with low T should address his testosterone shortage first and foremost. According to the findings of one study, low testosterone levels have a harmful influence on endothelial function and flow-mediated vasodilation even when other risk factors, such as hypertension, chronic smoking, and type 2 diabetes, are considered.

Men who suffer from low testosterone levels and erectile dysfunction almost always have a positive response to TRT. This is because TRT can restore both sex drive and erectile quality through changes in the body’s physiology and mind.


In addition to testosterone replacement therapy (if necessary), various drugs may be used to address erectile dysfunction. However, based on the etiology of erectile dysfunction, PDE5 inhibitors such as Viagra and Cialis are typically the most effective and convenient treatment options.


Viagra and Cialis are fast-acting and have long-lasting effects (up to 4 and 36 hours, respectively), but neither is addictive. So, you can think of Cialis as the “long-acting” version of Viagra.

If you have problems with the side effects of Cialis or Viagra, you may want to try avanafil (Stendra), a second-generation PDE5 inhibitor. Stendra’s maximal concentration is reached within about 30 minutes after administration, and its effects continue for around 2 hours, making it even faster than Cialis and Viagra. 

After taking a PDE5 inhibitor, some men may experience adverse effects such as nausea, headaches, or impaired vision, although these side effects usually go away once the medicine stops working. Due to their varying selectivities for PDE enzymes in various body parts, if one of the PDE5 drugs causes unwanted side effects, it is best to try another option. When compared to other male enhancement drugs like Viagra and Stendra, some men find that they can better handle Cialis.

Viagra and Cialis are non-habit-forming medications, and their effects have a rapid onset, usually lasting up to 4 hours and 36 hours, respectively.


If oral PDE5 inhibitors are ineffective, injectable medicines such as P-shot and Trimix may be recommended. These drugs are self-administered by injecting into the penis’ intracavernosal region, skipping the gastrointestinal process and causing an erection quickly.


Papaverine, phentolamine, and alprostadil are the three main chemicals that may be found in Trimix. These three ingredients work together to help dilate and relax the blood vessels in the penis. Because it has already been blended, the active ingredients must be maintained at a low temperature.

Injectable treatments for erectile dysfunction (ED) provide a number of benefits, one of which is that they do not readily interact with alcohol, food, or other drugs in the same way that PDE5 inhibitors can. In addition, injectable treatments for erectile dysfunction are also considered safe for men with cardiovascular conditions and diabetes.


P-Shot® for Treating Erectile Dysfunction The Priapus Shot® (P-Shot®) is an alternative injectable treatment for erectile dysfunction. Platelet-rich plasma (PRP) is injected multiple times into the penis in this one-time surgery to promote new tissue growth and better erections. Sexual endurance is boosted by the P-Shot® and is supposed to work in tandem with TRT. When performed under general anesthesia, the surgery takes less than 30 minutes and causes minimal discomfort to the patient. Some individuals may experience improvement right away, while for others, it may take up to three months.

When trying to decide which Erectile Dysfunction treatment is proper for you, it’s always best to go to a doctor who specializes in men’s health.



GameDay Men’s Health’s entire staff has undergone significant training in their respective fields to provide every one of our patients with the absolute best care possible every time.


A significant number of our rivals, who provide treatments that are analogous to the GainsWave, only give that treatment. At GameDay, we take a comprehensive approach to addressing your health concerns, including erectile dysfunction. We can provide same-day testosterone testing thanks to our cutting-edge on-site labs, which are located here. In addition, we do a diagnostic evaluation to identify the underlying cause of your ED, as opposed to taking educated guesses as many other healthcare practitioners do. When it comes to healthcare, it is always best to take a more holistic approach.


To ensure that our exclusive treatment regimen is always up to date with the most current scientifically proven knowledge that is at our disposal, our staff is constantly monitoring the publication of new research, conducting new tests, and reading contemporary literature. Because we have such a high success rate, we have been able to transform the lives of many men who previously believed they would never be able to have sexual encounters.


Men who struggle with erectile dysfunction rarely consider the possibility that low testosterone levels could be to blame. Although Viagra and Cialis are, without a doubt, helpful in treating erectile dysfunction, these medications will not address low testosterone levels. Maintaining a testosterone level optimal for your body is essential to your long-term health and fitness, as well as your sexual performance.

Under the direction of a qualified medical professional, TRT is just designed to “replenish” testosterone levels so that they are within a normal and healthy range. Therefore, only bioidentical testosterone, which is identical to the testosterone naturally produced by the body and is therefore considered safer, is utilized in GameDay Men’s Health’s treatments.

The adverse effects of testosterone are usually more severe when it is used illegally (i.e., for “performance enhancement”) than when it is used at safe TRT doses. TRT is, therefore, distinct from the practice of taking testosterone to improve physical performance.

Keep in mind that testosterone is a naturally occurring hormone essential to human health. A steady decline in health and quality of life results from a man’s body not producing enough of it.

TRT is simply meant to “replace” testosterone to a normal, healthy range under the guidance of a licensed physician.


Here are some of the most common questions and concerns we receive from prospective TRT candidates with erectile dysfunction:


The reality is that many of the purported risks of TRT, such as an increased risk of prostate cancer and cardiovascular disease, are based on results from poorly designed studies and flawed clinical trials.

In fact, several studies suggest that TRT is actually beneficial for cardiovascular function and metabolic health, which thereby promotes better erectile quality. Likewise, men with low T are the ones that have a greater risk of prostate issues than men with normal T levels.

What many people don’t know is that the amount of testosterone used for “performance enhancement” is drastically more than a proper TRT dose. A normal weekly dose of testosterone on TRT is anywhere from 100-200 mg.


There are a few side effects of TRT that some men with ED may experience, such as night sweating, oily skin, and acne (particularly on the shoulders or upper back). Thankfully, these side effects are easy to manage, if not avoid, by monitoring blood levels of various biomarkers and adjusting the TRT dose accordingly.

Any initial side effects of TRT generally subside after the body acclimates to having a normal, healthy level of testosterone again.


As part of our ED San Clemente Treatment, GameDay Men’s Health will ensure you get the best results possible while controlling any side effects.

PDE5 inhibitors like Viagra, Cialis, and Stendra are well-tolerated by most men and produce beneficial actions on erectile function quickly. For men with low T, these medications serve as great adjuncts to TRT for treating erectile dysfunction. Injectable medications, like the P-Shot and Trimix, are also safe and effective options when PDE5 inhibitors don’t produce the desired results.

If you’re experiencing ED or any other symptoms of low T, don’t hesitate to schedule a complimentary consultation with one of our hormone specialists by

or calling us at 858-252-9202

We’ve helped countless men regain their confidence and sexual vitality.


1. Selvin, E., Burnett, A. L., & Platz, E. A. (2007). Prevalence and risk factors for erectile dysfunction in the US. The American journal of medicine, 120(2), 151-157.
2. Laumann, E. O., Paik, A., & Rosen, R. C. (1999). Sexual dysfunction in the United States: prevalence and predictors. Jama, 281(6), 537-544.
3. Park, B., Wilson, G., Berger, J., Christman, M., Reina, B., Bishop, F., … & Doan, A. (2016). Is Internet pornography causing sexual dysfunctions? A review with clinical reports. Behavioral Sciences, 6(3), 17.
4. Hald, G. M. (2015). Comment on: Is pornography use associated with sexual difficulties and dysfunctions among younger heterosexual men?. The journal of sexual medicine, 12(5), 1140-1141.
5. Prause, N., & Pfaus, J. (2015). Viewing sexual stimuli associated with greater sexual responsiveness, not erectile dysfunction. Sexual medicine, 3(2), 90-98.
6. Traish, A. M., Guay, A., Feeley, R., & Saad, F. (2009). The dark side of testosterone deficiency: I. Metabolic syndrome and erectile dysfunction. Journal of andrology, 30(1), 10-22.
7. Zarrouf, F. A., Artz, S., Griffith, J., Sirbu, C., & Kommor, M. (2009). Testosterone and depression: systematic review and meta-analysis. Journal of Psychiatric Practice®, 15(4), 289-305.
8. Akishita, M., Hashimoto, M., Ohike, Y., Ogawa, S., Iijima, K., Eto, M., & Ouchi, Y. (2007). Low testosterone level is an independent determinant of endothelial dysfunction in men. Hypertension Research, 30(11), 1029.
9. Corona, G., Rastrelli, G., Vignozzi, L., Mannucci, E., & Maggi, M. (2011). Testosterone, cardiovascular disease, and the metabolic syndrome. Best practice & research Clinical endocrinology & metabolism, 25(2), 337-353.
10. Kloner, R. A., Carson, C., Dobs, A., Kopecky, S., & Mohler, E. R. (2016). Testosterone and cardiovascular disease. Journal of the American College of Cardiology, 67(5), 545-557.
11. Morgentaler, A. (2006). Testosterone replacement therapy and prostate risks: where’s the beef?. Canadian Journal of Urology, 13, 40.

It’s time to find the New You

Frequently Asked Questions

Why choose Gameday?

In contrast to many male health clinics, we offer a complimentary consultation that includes a blood test through our on-site laboratory. We will have your lab results ready within 15 minutes – no running around from building to building. Our expert, licensed staff specializes in treating male health and wellness. We are dedicated to providing you with the most professional care in a comforting, modern “man-cave” environment. To ensure optimal efficacy and safety, we use only the highest-quality medications, including bioidentical hormones that are the molecular equivalent of what your body naturally produces.

Why Gameday?
  1. On-site lab /get your results in 15 minutes/ No runaround/ free consultation
  2. Insurance Accepted / affordable
  3. Expert, licensed staff
  4. Comfortable ‘man-cave environment’
  5. Highest quality medication
What does TRT do?

Testosterone replacement therapy (TRT) is a form of medical treatment that helps restore testosterone levels to a healthy level by providing prescription testosterone. In most cases, injectable testosterone is administered either weekly or bi-weekly. This results in a steady supply of testosterone in the blood and, eventually, the reversal of low T symptoms. Hence, the goal of TRT is to re-establish and maintain proper testosterone levels. After being on TRT for a few weeks, many men notice they are able to sleep better, their sex drive is higher, they have more confidence and motivation, they have an easier time building muscle and losing fat, and their energy levels are greater. Adult males with low T are the ideal candidates for TRT since testosterone levels tend to fade as we age past our 20s. However, some younger males may be candidates for TRT if they have primary or secondary hypogonadism since these signify a dysfunction either in the testes or the brain, respectively. Regardless of what age you are, low T is not something to be taken lightly and TRT is the most effective way to treat this condition.

Where and how do I get my lab testing done?

We have an on-site laboratory that will perform any labs our physicians order for you. If you haven’t been to Gameday Men’s Health before, we offer a free consultation to new patients. You can book an appointment online by clicking here.

Can you help me with sexual dysfunction?

Sexual dysfunction related to low T is best remedied through TRT. Many men who have low T notice that they lose interest in sex and subsequently have a harder time achieving (and maintaining) an erection. Once testosterone levels are brought back to a healthy range, libido and erectile quality tend to improve. [We offer PDE5 inhibitors, like sildenafil and tadalafil, if erectile dysfunction persists despite having healthy testosterone levels.]

Are diet and exercise important?

Absolutely. Testosterone has extensive benefits when used in conjunction with a proper diet and diligent exercise regimen. Most men find that they are able to build more muscle and gain strength quicker when they are consistent with their nutrition plan and gym routine while on TRT. As such, it’s essential to realize that TRT is not intended to replace a healthy lifestyle. There is simply no drug, supplement, or medication that can make up for a poor diet and lack of exercise.