A New Look Testosterone Therapy

Gameday Men’s Health Lawrence
July 9, 2024
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Article / A New Look Testosterone Therapy

A New Look At Testosterone Therapy In [location_name]

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Over the past decade, TRT has become highly popular in [location_name]. Numerous older men have turned to this therapy to rejuvenate their hormone levels, hoping to boost their energy and revive their sexual drive.

Despite being widely utilized, TRT is a divisive issue due to uncertain benefits and potential health risks. Years ago, studies hinted at a possible link between TRT and a heightened risk of cardiovascular disease, causing safety concerns.

The limitations in some studies are pointed out by Dr. Frances Hayes, a reproductive endocrinologist at the Harvard-affiliated Massachusetts General Hospital.

“For instance, in one study, TRT doses were much higher than what would usually be prescribed, and the subjects tended to be more frail, with other health problems,” she says. “Other studies showed no evidence of increased risk.”

THE LATEST FINDINGS

Recent research supports this stance. Research presented at the 2015 American Heart Association Scientific Sessions involved 1,472 men aged 52 to 63 with low testosterone and no cardiovascular disease history.

The results showed that TRT did not heighten the risk of heart attack, stroke, or death in healthy men.

Research reported in the August 2015 Mayo Clinic Proceedings showed no association between TRT and blood clots in veins among 30,000 men. “Right now, the jury is still out about TRT’s influence on cardiovascular disease,” says Dr. Hayes.

The relationship between TRT and other health issues presents a mixed scenario. Despite earlier associations between TRT and a higher risk of prostate cancer, the December 2015 Journal of Urology published a study finding no increased risk of aggressive prostate cancer with five years of TRT exposure. This finding challenges traditional views and suggests further investigation into TRT’s long-term effects.

The long-term risks of TRT are still unknown, given the limited follow-up in many studies. However, individuals should not disregard TRT as a potential solution, as it may still be suitable for specific cases.

Who Is a Candidate For TRT In [location_name]?

Meeting two prerequisites is essential for receiving a TRT prescription in [location_name]: having low testosterone levels (below 600 nanograms per deciliter (ng/dL)) and experiencing various symptoms (refer to page 7). Dr. Hayes emphasizes, “While it’s possible to have low levels without symptoms, if key symptoms like fatigue and sexual dysfunction aren’t present, initiating TRT isn’t advisable due to current uncertainties regarding its long-term safety.”

Evaluating testosterone levels typically involves a standard blood test. Given the daily fluctuations and the influence of medication and diet, conducting multiple tests becomes necessary. Dr. Hayes mentions, “In about 30% of cases where the initial testosterone test indicates low levels, subsequent tests reveal normal levels.”

Low testosterone levels and encountering various symptoms don’t always warrant immediate testosterone replacement therapy (TRT). Dr. Hayes recommends, “Understanding the underlying cause of declining levels helps us address it and naturally boost low levels.”

Consider weight gain, for example, frequently the primary trigger for declining levels. “Weight has a more significant impact on testosterone levels than aging. As weight increases, testosterone levels tend to fall,” she stresses. A five-point jump on the body mass index (BMI) scale, such as moving from 30 to 35, equals adding 10 years to your age in terms of testosterone levels.

“Your doctor should also consider any additional factors that could influence levels, such as medication or medical conditions,” recommends Dr. Hayes. In such circumstances, your doctor may address the underlying cause or tweak your medication or dosage to prevent influencing testosterone levels.

Men should understand the confines of TRT, as it’s commonly celebrated as a miraculous solution. “Its outcomes are typically not as astounding as men expect,” Dr. Hayes observes.

As an example, sexual health and vitality are frequently highlighted as benefits of testosterone replacement therapy (TRT). A study in the Feb. 18, 2016 issue of The New England Journal of Medicine delved into how TRT impacted 790 men aged 65 and older. Those administered TRT for a year, as opposed to those on a placebo, observed enhancements in sexual function, including activity, desire, and erectile function. However, the group experienced only a slight uplift in mood and detected no changes in walking speed, indicating TRT’s limited impact on vitality.

Using TRT

TRT can be delivered via gel application or injection. When using gel, the daily dose, about the size of a ketchup packet, is evenly distributed over both upper arms, shoulders, or thighs. Injections are typically given into the buttocks every two weeks.

Each method presents specific advantages, with gels ensuring consistent testosterone levels. “However, you should be careful to avoid close skin contact for a few hours, especially with women, as testosterone could cause acne or hair growth,” Dr. Hayes advises.

Post-injection, testosterone levels may briefly surge before gradually decreasing, resulting in mood and energy fluctuations similar to a roller-coaster effect.

Most men in [location_name] typically notice symptom improvement within four to six weeks, although muscle mass changes may take three to six months.

TRT doesn’t necessarily need to be permanent. “If the factor that caused your testosterone drop is resolved, you should try stopping the treatment and be re-evaluated by your doctor,” says Dr. Hayes.

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