A New Look Testosterone Therapy

Gameday Men’s Health Appleton
August 29, 2024
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Article / A New Look Testosterone Therapy

A New Look At Testosterone Therapy In [location_name]

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Over the past decade, the trend of testosterone replacement therapy (TRT) has significantly grown in Appleton. Numerous older men have turned to this therapy to restore their hormone levels, aiming to boost their vitality and revive their sexual desire.

Although TRT is widely used, it remains a controversial matter due to uncertain benefits and potential health risks. Research from years ago suggested a possible connection between TRT and a higher risk of cardiovascular disease, leading to safety concerns.

At the Harvard-affiliated Massachusetts General Hospital, Dr. Frances Hayes, a Reproductive Endocrinologist, identifies the limitations in some studies.

“For instance, in one study, TRT doses were much higher than what would usually be prescribed, and the subjects tended to be more frail, with other health problems,” she says. “Other studies showed no evidence of increased risk.”

THE LATEST FINDINGS

New research upholds this viewpoint. At the 2015 American Heart Association Scientific Sessions, a study of 1,472 men aged 52 to 63 with low testosterone levels and no cardiovascular disease history found that TRT did not elevate the risk of heart attack, stroke, or death in healthy men.

The August 2015 Mayo Clinic Proceedings provided further findings showing no link between TRT and blood clots in veins among 30,000 men. “Right now, the jury is still out about TRT’s influence on cardiovascular disease,” says Dr. Hayes.

TRT’s association with other health issues is varied. Although past studies suggested a higher risk of prostate cancer with TRT, a December 2015 Journal of Urology study showed no increased risk of aggressive prostate cancer with five years of TRT exposure. This challenges conventional understanding and highlights the need for further investigation into TRT’s long-term effects.

Because of limited follow-up in numerous studies, TRT’s long-term risks remain unclear. Nonetheless, TRT should not be overlooked as a potential solution, as it may be suitable for certain individuals.

Who Is a Candidate For TRT In [location_name]?

In Appleton, two prerequisites are required for TRT prescription: low testosterone levels (below 600 nanograms per deciliter (ng/dL)) and experiencing multiple symptoms (refer to page 7). Dr. Hayes emphasizes, “While it’s conceivable to have low levels without symptoms, if crucial symptoms like fatigue and sexual dysfunction aren’t present, initiating TRT isn’t advisable due to current uncertainties surrounding its long-term safety.”

A typical blood test is frequently used to measure testosterone levels. Given daily fluctuations and the influence of medication and diet, multiple tests are necessary. Dr. Hayes explains, “In around 30% of cases where the initial testosterone test indicates low levels, subsequent tests show normal levels.”

Testosterone replacement therapy (TRT) may not always be the immediate solution, even with low testosterone levels and various symptoms. Dr. Hayes suggests, “By understanding the underlying cause of declining levels, we can address it and naturally enhance low levels.”

As an example, improvements in sexual well-being and vitality are often highlighted as benefits of TRT. According to a study published in the February 18, 2016 edition of The New England Journal of Medicine, 790 men aged 65 and older were studied to assess TRT’s effects. Those who received TRT for one year, compared to those on a placebo, noted enhancements in sexual function, including activity, desire, and erectile function. However, the group experienced only minimal improvements in mood and observed no changes in walking speed, which is an indicator of TRT’s effect on vitality.

“Your doctor should also consider any additional factors that could influence levels, such as medication or medical conditions,” advises Dr. Hayes. In such cases, your doctor might address the primary cause or adjust your medication or dosage to prevent affecting testosterone levels.

It’s essential for men to understand the limitations of TRT, commonly portrayed as a cure-all. “Its outcomes are typically not as astounding as men expect,” Dr. Hayes observes.

This is exemplified by the frequent emphasis on sexual health and vitality as benefits of testosterone replacement therapy (TRT). A study featured in the February 18, 2016 release of The New England Journal of Medicine examined the effects of TRT on 790 men aged 65 and older. Those who received TRT for one year, compared to those on a placebo, reported improvements in sexual function, including activity, desire, and erectile function. However, the group experienced only a marginal improvement in mood and observed no changes in walking speed, a gauge of TRT’s effect on vitality.

Using TRT

TRT can be administered via gel application or injections. Gel application entails applying a daily dose, about the size of a ketchup packet, to both upper arms, shoulders, or thighs. Injections are typically given into the buttocks every two weeks.

Both methods offer advantages, with gels known for their ability to stabilize testosterone levels. “However, you should be careful to avoid close skin contact for a few hours, especially with women, as testosterone could cause acne or hair growth,” Dr. Hayes advises.

Post-injection, testosterone levels may briefly spike before tapering off, causing mood and energy fluctuations similar to a roller-coaster.

In Appleton, most men typically notice symptom improvement within four to six weeks, though changes in muscle mass may take three to six months.

It’s worth noting that TRT doesn’t necessarily need to be lifelong. “If the factor that caused your testosterone drop is resolved, you should try stopping the treatment and be re-evaluated by your doctor,” says Dr. Hayes.

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